Ontores/Annexin 1（ANXA-1，Ac 2-26）/1mg/ONP10032
商品编号：
ONP10032
品牌：
ontorespeptide
市场价：
¥3600.00
美元价：
1800.00
产品分类：
免疫组化
公司分类：
immunohistochemical
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionThis acetylated peptide is amino acids 2 to 28 N-terminus fragment of Annexin 1 (ANXA1). ANXA1, previously referred to as lipocortin 1 or LC1, is a member of the annexin superfamily that has potent leukocyte antimigratory activity. This fragment, as well as the full-length ANXA1, may significantly reduce polymorphonuclear leukocyte (PMN) influx in mice. ANXA1 and ANXA1 mimetics, such as Ac (2-12), inhibit recruitment of neutrophils in acute and chronic inflammation. This peptide is able to inhibit neutrophil extravasation.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10032
CAS No.151988-33-9
NameAnnexin 1 (ANXA - 1, Ac 2 - 26)
Chemical NameAnnexin-1-(ANXA---1,-Ac-2---26)
Purity≥98%
SynonymsAnnexin-1 (2-26) (human)； Lipocortin-1 (2-26)； Calpactin II (1-25) (dephosphorylated) (human)； Ac2-26
FormulaC141H210N32O44S
Molecular Weight3041.4
One Letter CodeAc-AMVSEFLKQAWIENEEQEYVVQTVK
Three Letter CodeAc-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Val-Gln-Thr-Val-Lys-OH
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.Human neutrophil formyl peptide receptor phosphorylation and the mucosal inflammatory response.
2.Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice.
3.Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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