Ontores/Dermaseptin/0.5mg/ONP10033
商品编号：
ONP10033
品牌：
ontorespeptide
市场价：
¥3140.00
美元价：
1570.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionDermaseptins are antimicrobial peptides, strings of amino acids, or proteins, of various sizes and shapes. Dermaseptins were isolated from frog skin. Dermaseptin is a crucial part of the frog"s immune system, inhibiting the growth of bacteria, protozoa and fungi. Dermaseptins are cationic (positively charged) and 27-34 residues in length. Dermaseptins adopt a largely K-helical conformation when binding to membranes. Like other antimicrobial peptides, dermaseptin is membrane-perturbing; however, unlike other antimicrobial peptides, dermaseptin rests on the surface of the bacterial membrane and does not insert.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10033
CAS No.136033-70-0
NameDermaseptin
Chemical NameDermaseptin
Purity≥98%
SynonymsN/A
FormulaC152H257N43O44S2
Molecular Weight3455.1
One Letter CodeALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Three Letter CodeALA-LEU-TRP-LYS-THR-MET-LEU-LYS LYS-LEU-GLY-THR-MET-ALA-LEU-HIS ALA-GLY-LYS-ALA-ALA-LEU-GLY-ALA ALA-ALA-ASP-THR-ILE-SER-GLN-GLY THR-GLN
SMILESCCC(C)C(C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C)NC(=O)C(CC1=CN=CN1)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC(C)C)NC(=O)C(C)N
InChI KeyYFHLIDBAPTWLGU-CTKMSOPVSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Pinto EGet al. Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi. Exp Parasitol 135:655-60 (2013).
2.A.Mor et al., Biochemistry, 30, 8824 (1991)
3.Savoia Det al. In vitro activity of dermaseptin S1 derivatives against genital pathogens. APMIS 118:674-80 (2010).
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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