Ontores/Parasin I/0.5mg/ONP10044
商品编号：
ONP10044
品牌：
ontorespeptide
市场价：
¥1800.00
美元价：
900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionParasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). Eighteen of the 19 residues in parasin I are identical to the N-terminus of buforin I, a 39-residue antimicrobial peptide derived from the N-terminus of toad histone H2A. This implies that parasin I is cleaved off of the N-terminus of catfish histone H2A. Parasin I shows strong antimicrobial activity, about 12-100 times as strong as magainin 2, against a wide spectrum of microorganisms, without any hemolytic activity. Furthermore, parasin I shows good antimicrobial activity against fish-specific bacterial pathogens.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10044
CAS No.219552-69-9
NameParasin I
Chemical NameParasin-I
Purity≥98%
SynonymsN/A
FormulaC82H154N34O24
Molecular Weight2000.3
One Letter CodeKGRGKQGGKVRAKAKTRSS
Three Letter CodeLYS-GLY-ARG-GLY-LYS-GLN-GLY-GLY-LYS-VAL-ARG-ALA-LYS-ALA-LYS-THR-ARG-SER-SER
SMILESCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCCN)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCCCN)N
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Koo YSet al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides 29:1102-8 (2008).
2.Cho JHet al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB J 16:429-31 (2002).
3.Cho JHet al. Matrix metalloproteinase 2 is involved in the regulation of the antimicrobial peptide parasin I production in catfish skin mucosa. FEBS Lett 531:459-63 (2002).
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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