Ontores/HIF-1 alpha (556-574)/1mg/ONP10079
商品编号：
ONP10079
品牌：
ontorespeptide
市场价：
¥1800.00
美元价：
900.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionThis is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely vital to the binding process.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10079
CAS No.N/A
NameHIF-1 alpha (556-574)
Chemical NameHIF-1-alpha-(556-574)
Purity≥98%
SynonymsHypoxia-inducible factor 1-alpha； HIF-1-alpha； HIF1-alpha； hif1a
FormulaN/A
Molecular Weight2254.6
One Letter CodeDLDLEMLAPYIPMDDDFQL
Three Letter CodeAsp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1. T. Bondeva, J. Heinzig, S. Franke, G. Wolf.Angiotensin II Differentially Regulates Morg1 Expression in Kidney Cells.Am J Nephrol 2012;35:442-455
2.M. Hirsila, P. Koivunen, L. Xu, T. Seeley, K. I. Kivirikko, and J. Myllyharju.Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway.The FASEB Journal. 2005;19:1308-1310.
3.M. Hirsila, P. Koivunen, V. Gunzler, K. I. Kivirikko, and J. Myllyharju. Characterization of the Human Prolyl 4-Hydroxylases That Modify the Hypoxia-inducible Factor.J. Biol. Chem., August 15, 2003; 278(33): 30772 - 30780.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
联络我们
