Ontores/Gly-Arg-Gly-Asn-Pro/25mg/ONP10535
商品编号：
ONP10535
品牌：
ontorespeptide
市场价：
¥480.00
美元价：
240.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionG-R-G-D-N-P is a superior inhibitor of cell attachment to fibronectin and a weak inhibitor of cell attacment to vitronectin. It also inhibits binding of fibrinogen, fibronectin, vitronectin and von Willebrand factor to platelets and resists to carboxypeptidases. G-R-G-D-N-P induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. It contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. G-R-G-D-N-P inhibits cell adhesion to fibronectin 80-90% at 1 mM.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10535
CAS No.114681-65-1
NameGly-Arg-Gly-Asp-Asn-Pro
Chemical NameGly-Arg-Gly-Asp-Asn-Pro
Purity≥98%
SynonymsN/A
FormulaC23H38N10O10
Molecular Weight614.6
One Letter CodeGRGDNP
Three Letter CodeGLY-ARG-GLY-ASP-ASN-PRO
SMILESC1CC(N(C1)C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)O
InChI KeyCWAHAVYVGPRZJU-XUXIUFHCSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.M.A.Peake et al., J. Appl. Physiol., 89, 2498 (2000)
2.J.E.Mogford et al., J. Clin. Invest., 100, 1647 (1997)
3.Sarin V, et al. Arginine-glycine-aspartic acid (RGD)-containing peptides inhibit the force production of mouse papillary muscle bundles via alpha 5 beta 1 integrin. J. Physiol. Apr 2005; 564(Pt 2): 603-617.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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