Ontores/β-黑素细胞刺激素（MSH），人/25mg/ONP10544
商品编号：
ONP10544
品牌：
ontorespeptide
市场价：
¥1800.00
美元价：
900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionAlpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10544
CAS No.17908-57-5
Nameβ-Melanocyte Stimulating Hormone (MSH), human
Chemical Nameβ-Melanocyte-Stimulating-Hormone-(MSH),-human
Purity≥98%
Synonymsbeta melanocyte stimulating hormoneβ-MSH； human
FormulaC118H174N34O35S
Molecular Weight2661
One Letter CodeAEKKDEGPYRMEHFRWGSPPKD
Three Letter CodeALA-GLU-LYS-LYS-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP
SMILESCC(C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)N1CCCC1C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC=N3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NCC(=O)NC(CO)C(=O)N7CCCC7C(=O)N8CCCC8C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)O)N
InChI KeyXLLJFSCSXTYVTN-UPWOUFKKSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Blagaić V, Houra K, Turcić P, et al. The influence of alpha-, beta-, and gamma-melanocyte stimulating hormone on acetaminophen induced liver lesions in male CBA mice. Molecules. 2010 Mar 3;15(3):1232-41. PMID: 20335976
2.Kamisoyama H, Honda K, Saneyasu T, et al. Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks. Neurosci Lett. 2009 Jul 24;458(3):102-5. PMID: 19393716
3.Leder EH, Silverstein JT. The pro-opiomelanocortin genes in rainbow trout (Oncorhynchus mykiss): duplications, splice variants, and differential expression. J.Endocrinol. Feb 2006; 188(2): 355-363
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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