Ontores/蛙皮素/25mg/ONP10585
商品编号：
ONP10585
品牌：
ontorespeptide
市场价：
¥480.00
美元价：
240.00
产品分类：
病毒抗原
公司分类：
Virus_antigen
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionBombesin is a 14 amino acid peptide originally isolated from the skin of a frog. Bombesin has two known homologues in mammals called neuromedin B and gastrin releasing peptide. Bombesin works on the gastrointestinal tract neuroendocrine hormone and bombesin stimulates gastrin release from G cells. Bombesin activates three different G-protein coupled receptors known as BBR1 2 and 3. Bombesin also activates these receptors in the brain. Together with cholecystokinin bombesin is the second major source of negative feedback signals that stop eating behavior.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10585
CAS No.31362-50-2
NameBombesin
Chemical NameBombesin
Purity≥98%
SynonymsN/A
FormulaC71H110N24O18S
Molecular Weight1619.9
One Letter CodeN/A
Three Letter CodeGLP-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
SMILESO=C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)CC1=CN=CN1)=O)=O)=O)C)[C@@H](NC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC(CNC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H]2CCC(N2)=O)=O)CCC(N)=O)=O)=O)CC(C)C)=O)=O)=O)=O)CC3=CNC4=C3C=CC=C4
InChI KeyQXZBMSIDSOZZHK-DOPDSADYSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Blais et al (2016) Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin Neuroscience Letters 633 262 PMID: 27693662
2.Solorzano et al (2015) Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci 35 648 PMID: 25589759
3.Weber, H.C. Regulation and signaling of human bombesin receptors and their biological effects. Curr. Opin. Endocrinol. Diabetes Obes. 16(1), 66-71 (2009)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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