Ontores/N-甲酰-Met-Leu-Phe/0.5mg/ONP10601
商品编号：
ONP10601
品牌：
ontorespeptide
市场价：
¥560.00
美元价：
280.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionN-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very high concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and highly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10601
CAS No.59880-97-6
NameN-Formyl-Met-Leu-Phe
Chemical NameN-Formyl-Met-Leu-Phe
Purity≥98%
SynonymsN/A
FormulaC21H31N3O5S
Molecular Weight437.56
One Letter CodeN-Formyl-MLF
Three Letter CodeN-Formyl-MET-LEU-PHE
SMILESCC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CCSC)NC=O
InChI KeyPRQROPMIIGLWRP-BZSNNMDCSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Mills JSet al. Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu. J Biol Chem 275:39012-7 (2000). Read more (PubMed: 10960471)
2.Le Yet al. Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors. Immunol Rev 177:185-94 (2000). Read more (PubMed: 11138775)
3.Katada Tet al. Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors. Chem Phys Lipids 98:79-86 (1999). Read more (PubMed: 10358930)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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