Ontores/IRBP (1-20), human/5mg/ONP10787
商品编号:
ONP10787
品牌:
ontorespeptide
市场价:
¥1400.00
美元价:
700.00
产品分类:
组织标本
公司分类:
Tissue_samples
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionThis peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1 – 20) induces T-cell–mediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10787
CAS No.N/A
NameIRBP (1-20), human
Chemical NameIRBP-(1-20),-human
Purity≥98%
SynonymsN/A
FormulaC101H164N24O28S1
Molecular Weight2194.6
One Letter CodeGPTHLFQPSLVLDMAKVLLD
Three Letter CodeGly-Pro-Thr-His-Leu-Phe-Gln-Pro-Ser-Leu-Val-Leu-Asp-Met-Ala-Lys-Val-Leu-Leu-Asp
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.Avichezer, D. et al. Invest. Ophthalmol. Visual Sci. 41, 127 (2000)
2.Lee DJ., et al. Both MC5r and A2Ar Are Required for Protective Regulatory Immunity in the Spleen of Post–Experimental Autoimmune Uveitis in Mice. J Immunol. 2013 Qct;191(8):4103-11.
3.Darren J. Lee and Andrew W. Taylor.., et al. Following Eau Recovery There Is An Associated Mc5R-Dependent Apc Induction Of Regulatory Immunity In The Spleen. Invest Ophthalmol Vis Sci. 2011 Nov;52(12):8862-7
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售,数百种处于临床开发的不同阶段。肽由于具有分子量小,靶向选择性高,活性高,毒性低,易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大,越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范(cGMP)制造的能力以及用于小型非GMP定制肽的能力,ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品,努力超越预期。ONTORES提供灵活的批量大小,从小规模到大规模生产,包括合成,纯化和冻干。
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