Ontores/促甲状腺激素释放激素（TRH），游离酸/5mg/ONP10873
商品编号：
ONP10873
品牌：
ontorespeptide
市场价：
¥480.00
美元价：
240.00
产品分类：
其它天然蛋白
公司分类：
Other_natural_proteins
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionTRH free acid is derived from Thyrotropin Releasing Hormone (TRH), and the latter could cause the release of Thyroid Stimulating Hormone (TSH) from the pituitary and was isolated in pure form and the structure determined. They are different functionally, such as stimulation of GTPase depended on occupancy of the TRH receptor; half-maximal increases in GTPase activity required 46 nM TRH and 25 nM [N3-methyl-His]TRH, but the TRH free acid was inactive.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10873
CAS No.24769-58-2
NameThyrotropin-Releasing Hormone (TRH), Free Acid
Chemical NameThyrotropin-Releasing-Hormone-(TRH),-Free-Acid
Purity≥98%
SynonymsN/A
FormulaC16H21N5O5
Molecular Weight363.37
One Letter CodepEHP
Three Letter CodepGLU-HIS-PRO
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.
2.Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.
3.Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售，数百种处于临床开发的不同阶段。肽由于具有分子量小，靶向选择性高，活性高，毒性低，易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大，越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范（cGMP）制造的能力以及用于小型非GMP定制肽的能力，ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品，努力超越预期。ONTORES提供灵活的批量大小，从小规模到大规模生产，包括合成，纯化和冻干。
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