Ontores/Ac-YVAD-AFC/5mg/ONP10917
商品编号:
ONP10917
品牌:
ontorespeptide
市场价:
¥3440.00
美元价:
1720.00
产品分类:
引物与探针
公司分类:
Primer_Probe
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
BIOLOGICAL INFORMATION
DescriptionAc-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.1,2 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10917
CAS No.219137-85-6
NameAc-YVAD-AFC
Chemical NameAc-YVAD-AFC
Purity≥98%
SynonymsN/A
FormulaC33H36F3N5O10
Molecular Weight719.67
One Letter CodeAc-YVAD-AFC
Three Letter CodeAc-Tyr-Val-Ala-Asp-AFC
SMILESCC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C
InChI KeyGWKJISJKNKIJNP-UHFFFAOYSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Talanian, R.V.,Quinlan, C.,Trautz, S., et al. Substrate specificities of caspase family proteases. The Journal of Biological Chemisty 272(15), 9677-9682 (1997).
2.Marcelli, M.,Cunningham, G.R.,Haidacher, S.J., et al. Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP. Cancer Research 58(1), 76-83 (1998).
3.Jones et al (1998) Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases. Hepatology 27 1632 PMID: 9620337
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
品牌介绍
cGMP肽合成服务肽在临床应用中的使用逐年增加。数十种肽已作为药物销售,数百种处于临床开发的不同阶段。肽由于具有分子量小,靶向选择性高,活性高,毒性低,易于渗透和吸收等突出特点而被用作药物。随着市场规模的不断扩大,越来越多的公司选择参与这一市场。凭借其能够进行商业化的良好生产规范(cGMP)制造的能力以及用于小型非GMP定制肽的能力,ONTORES可以满足从研究到商业化的药物肽开发各个阶段的需求。ONTORES是您值得信赖的高度复杂肽源。我们通过不断投资开发可提供最高质量肽段的专有化学产品,努力超越预期。ONTORES提供灵活的批量大小,从小规模到大规模生产,包括合成,纯化和冻干。
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